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The Middle Coarno Organism

A synthetic biological enterprise for life and health

The Middle Coarno Organism
Nako Arnault

Make life healthier and more beautiful

Nako Arnault
The Middle Coarno Organism

Integrity, performance, responsibility, innovation, harmony

The Middle Coarno Organism
The Middle Coarno Organism

Focus on the development of anti-aging, anti-tumor, immune-enhancing bioactive substances

The Middle Coarno Organism
The Middle Coarno Organism

Targeting the global synthetic biotechnology frontier

The Middle Coarno Organism

Enter the Middle Coarno Creature

Zhongko Arnault (Shenzhen) Biotechnology Co., Ltd. is a life oriented synthetic biological enterprise, adhering to the vision and mission of "making life healthier and more beautiful", using synthetic biotechnology and cell factory to research and develop a series of high value-added bioactive substances that are anti-aging, anti-tumor and enhance immunity. It is committed to providing innovative raw materials and solutions for nutrition and health care, new drug research and development and medical beauty skin care, serving functional health food, pharmaceutical manufacturing, cosmetics enterprises and related end users around the world.

Cutting-edge synthetic biology and engineered cell factory technology

Based on synthetic biotechnology, relying on strong scientific research capabilities, develop "editable, controllable and applicable" chassis cells, create an engineered cell factory, cultivate and domesticate innovative germplasm more suitable for industrialization, and lay the foundation for the industrial application of synthetic biological manufacturing technology

Multifunctional modular synthetic biological intelligent system

After more than 10 years of research and accumulation of synthetic biology technology, the synthetic biological manufacturing technology and process with independent intellectual property rights have broken through the bottleneck of large-scale production of aseptic and non-heavy metal pollution under controlled conditions, and established an exclusively designed biological fermentation system, which has been put into operation.

Prospective bioactive material matrix layout

With multiple advantages and values such as efficiency improvement, cost reduction, energy saving and raw material recycling, it is on the eve of industrial expansion, adhering to market orientation and application orientation, application batch, research and development batch, reserve batch; Focus on technology "one move first", integration and innovation of production, university and research, and continuous iteration and upgrading of technology.

Clear B2B2C innovative business model

The market direction of providing innovative raw materials and solutions is clear, the commercialization path is mature, the product form is clear, and the development of bioactive raw materials is mainly 2B business; Targeted to develop 2C products related to bioactive substances for the brand; Continue to develop self-branded 2C products such as doctoral articles and BOSHI DAILY.

BRANDS & PRODUCTS

Brand and product

Bioactive material raw materials | end products

Biological active material raw material

ARNOGLENA™, ARNOGLU™, ARNOPALAMYLON™, etc

Functional food

BOSHI DAILY™, Daily Food ™, etc

Functional skin care product

Anti-wrinkle and anti-aging, such as PhD ® and Streamline ®

With the development of modern genetic technology, scientists seem to have uncovered the mystery of human aging, a variety of anti-aging drugs emerge in endless variety, its effect can be seen. Although it does not make humans immortal, it can make people healthy and long life, which is also to make the myth become a reality. In fact, with the development of human anti-aging medicine, scientists have revealed such a new concept: human aging is not irresistible, the aging of the human body itself is a disease.

Honey contains a large number of amino acids, enzymes, hormones, vitamins and sugars that can be absorbed by the human body, and has the beauty effect of nourishing skin care. With honey and 2-3 times water dilution, daily application, can make the skin smooth, delicate.

Drink at least 2000cc of water a day, when the body fat burning use, need to have enough water to expel these metabolites. It is very easy to dehydrate during weight loss, so water supplementation is more important

Some maintenance substances may be very suitable for Western women's skin, and have good effects in skin repair, maintenance and anti-aging, but for eastern women, some small differences may cause skin maintenance anti-aging to lose its due effect.

Clinical practice has also shown that through treatment, the aging process of the human body can not only be delayed but also reversed! Cells mean life to people, and the birth and death of cells is also a process of human body aging. The growth of cells depends on division, and once the rate of cell division slows down, it indicates the reduction of new cells, which is the beginning of aging that everyone fears, so the fundamental prevention of aging ultimately comes down to cells. Today, people use the active cells in sheep embryosin to help restore the activity of aging cells, accelerate the division of human cells, and thus increase the number of new cells.

Cosmetics are used for healthy skin almost every day, so they must ensure the safety of long-term use on the human body, that is, non-toxic, non-irritating, and non-mutagenic disease-causing effects.

INFORMATION CENTER

08-18

2023

All relevant units: Diet is better for metabolic health and anti-aging

Modifying diet may be more effective than taking drugs at controlling conditions such as diabetes, stroke and heart disease, according to an Australian preclinical study. The study showed that nutrition, including total calories and macronutrient balance, has a greater impact on aging and metabolic health than the three commonly used diabetes and anti-aging drugs. The results were published in Cell Metabolism. The study builds on the team's pioneering work in mice and humans, demonstrating the protective effects of diet and specific combinations of protein, fat, and carbohydrates on the risk of aging, obesity, heart disease, immune dysfunction, and metabolic diseases such as type 2 diabetes. There has been an ongoing effort to find drugs that improve metabolic health and aging without changing diet. "Diet is good medicine. However, drugs are currently administered without considering whether and how they can interact with dietary components - even though these drugs act in the same way and nutritional signaling pathways as diet." Professor Stephen Simpson, corresponding author of the paper and academic director of the Charles Perkins Centre at the University of Sydney. So the researchers set out to see whether drugs or diets were more effective at reshaping nutrient perception and other metabolic pathways, and whether interactions between drugs and diets made them more effective. The team designed a complex mouse study that included 40 different approaches, each with different amounts of protein, fat and carbohydrates, calories and drugs. The study was designed to examine the effects of three anti-aging drugs on the liver, a key organ that regulates metabolism. A key strength of the study is the use of a nutritional geometric framework developed by Simpson and colleague David Raubenheimer. This framework allows researchers to consider how mixtures and interactions of different nutrients affect health and disease, rather than focusing on any one nutrient in isolation - a limitation of other nutrition studies. "We found that diet has a much stronger effect than drugs. Drugs largely suppress people's responses to diet rather than reshape them." "Given that humans and mice essentially share the same nutritional signaling pathways, the study suggests that people who change their diet to improve their metabolic health may have better results than if they were taking a drug," Simpson said. The findings help to understand the mechanisms between what we eat and how we age. Studies have found that calorie intake and the balance of macronutrients (protein, fat, and carbohydrates) in the diet have a big impact on the liver. Protein and total calorie intake have a particularly large impact on metabolic pathways and the basic processes that control cell function. For example, the amount of protein consumed affects the activity of the mitochondria, the part of the cell that produces energy. This creates a downstream effect, as the intake of protein and dietary energy affects the accuracy with which cells convert their genes into different proteins (which help cells function properly and make new cells), both of which are fundamental processes involved in aging. Drugs, by contrast, work primarily by inhibiting the cells' metabolic response to diet, rather than fundamentally reshaping them. However, the researchers also found some more specific interactions between the biochemical effects of drugs and dietary components. One anti-aging drug had a greater effect on cellular changes caused by dietary fats and carbohydrates, while a cancer drug and another diabetes drug both blocked the effects of dietary proteins on energy-producing mitochondria. David Le Couteur, one of the authors of the paper and a professor at the Charles Perkins Center, said that although the study is very complex, it shows how important it is to look at many different diets at once, rather than just comparing several different diets. "We all know that what we eat affects health, but this study shows that food can significantly affect many processes in the cells of the human body." This gives us insight into how diet affects health and aging."

CONTACT

Zhongke Arnaud (Shenzhen) Biotechnology Co., LTD

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